Identification and characterization of extrachromosomal circular DNA in maternal plasma

We explored the presence of extrachromosomal circular DNA (eccDNA) in the plasma of pregnant women. Through sequencing following either restriction enzyme or Tn5 transposase treatment, we identified eccDNA molecules in the plasma of pregnant women. These eccDNA molecules showed bimodal size distribu...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Sin, Sarah T. K., Jiang, Peiyong, Deng, Jiaen, Ji, Lu, Cheng, Suk Hang, Dutta, Anindya, Leung, Tak Y., Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2020
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983429/
https://ncbi.nlm.nih.gov/pubmed/31900366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914949117
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