Identification and characterization of extrachromosomal circular DNA in maternal plasma

We explored the presence of extrachromosomal circular DNA (eccDNA) in the plasma of pregnant women. Through sequencing following either restriction enzyme or Tn5 transposase treatment, we identified eccDNA molecules in the plasma of pregnant women. These eccDNA molecules showed bimodal size distribu...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Sin, Sarah T. K., Jiang, Peiyong, Deng, Jiaen, Ji, Lu, Cheng, Suk Hang, Dutta, Anindya, Leung, Tak Y., Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983429/
https://ncbi.nlm.nih.gov/pubmed/31900366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914949117
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