Identification and characterization of extrachromosomal circular DNA in maternal plasma

We explored the presence of extrachromosomal circular DNA (eccDNA) in the plasma of pregnant women. Through sequencing following either restriction enzyme or Tn5 transposase treatment, we identified eccDNA molecules in the plasma of pregnant women. These eccDNA molecules showed bimodal size distribu...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Sin, Sarah T. K., Jiang, Peiyong, Deng, Jiaen, Ji, Lu, Cheng, Suk Hang, Dutta, Anindya, Leung, Tak Y., Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2020
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983429/
https://ncbi.nlm.nih.gov/pubmed/31900366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914949117
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