Wordt geladen...
Trimethoprim: An Old Antibacterial Drug as a Template to Search for New Targets. Synthesis, Biological Activity and Molecular Modeling Study of Novel Trimethoprim Analogs
A new series of trimethoprim (TMP) analogs containing amide bonds (1–6) have been synthesized. Molecular docking, as well as dihydrofolate reductase (DHFR) inhibition assay were used to confirm their affinity to bind dihydrofolate reductase enzyme. Data from the ethidium displacement test showed the...
Bewaard in:
| Gepubliceerd in: | Molecules |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
MDPI
2019
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6983048/ https://ncbi.nlm.nih.gov/pubmed/31892256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25010116 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|