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1,3,5-Triazine Nitrogen Mustards with Different Peptide Group as Innovative Candidates for AChE and BACE1 Inhibitors

A series of new analogs of nitrogen mustards (4a–4h) containing the 1,3,5-triazine ring substituted with dipeptide residue were synthesized and evaluated for the inhibition of both acetylcholinesterase (AChE) and β-secretase (BACE1) enzymes. The AChE inhibitory activity studies were carried out usin...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Maliszewski, Dawid, Wróbel, Agnieszka, Kolesińska, Beata, Frączyk, Justyna, Drozdowska, Danuta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8271926/
https://ncbi.nlm.nih.gov/pubmed/34203347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26133942
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