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A novel medium size lactam ring analoges as antibacterial agents: Synthesis, biological evaluation and molecular docking studies
A novel series of medium size (S)-3-alkyl-3,4,6,7-tetrahydro-1H-benzo[e][1,4]diazonine-2,5-dione (6a-f) analogues were synthesized from (E)-3-(2-nitrophenyl)acrylicacid (2) reacting with various amino acid esters using Di-isopropyl Carbodiimide as a coupling agent. The final cyclization is carried o...
Enregistré dans:
| Publié dans: | EXCLI J |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Leibniz Research Centre for Working Environment and Human Factors
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5735333/ https://ncbi.nlm.nih.gov/pubmed/29285005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2017-193 |
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