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Synthesis and biological evaluation of rapamycin-derived, next generation small molecules
Over the years, rapamycin has attracted serious attention due to its remarkable biological properties and as a potent inhibitor of the mammalian target of rapamycin (mTOR) protein through its binding with FKBP-12. Several efficient strategies that utilize synthetic and biosynthetic approaches have b...
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| Vydáno v: | Medchemcomm |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Royal Society of Chemistry
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072512/ https://ncbi.nlm.nih.gov/pubmed/30108899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00474e |
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