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Autophagy Deficiency in Renal Proximal Tubular Cells Leads to an Increase in Cellular Injury and Apoptosis under Normal Fed Conditions

Renal proximal tubular epithelial cells are significantly damaged during acute kidney injury. Renal proximal tubular cell-specific autophagy-deficient mice show increased sensitivity against renal injury, while showing few pathological defects under normal fed conditions. Considering that autophagy...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Suzuki, Chigure, Tanida, Isei, Oliva Trejo, Juan Alejandro, Kakuta, Soichiro, Uchiyama, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982095/
https://ncbi.nlm.nih.gov/pubmed/31881660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010155
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