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Autophagy protects proximal tubular cells from injury and apoptosis
Autophagy is upregulated during ischemia–reperfusion (IR)-induced and cisplatin-induced acute kidney injury (AKI). Proximal tubule-specific Atg7 knockout mice exhibited increased renal injury compared with wild-type mice following cisplatin- and IR-induced AKI. Inhibition of autophagy by chloroquine...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4068008/ https://ncbi.nlm.nih.gov/pubmed/23203020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.337 |
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