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Autophagy protects proximal tubular cells from injury and apoptosis

Autophagy is upregulated during ischemia–reperfusion (IR)-induced and cisplatin-induced acute kidney injury (AKI). Proximal tubule-specific Atg7 knockout mice exhibited increased renal injury compared with wild-type mice following cisplatin- and IR-induced AKI. Inhibition of autophagy by chloroquine...

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Bibliografiske detaljer
Hovedforfatter: Kaushal, Gur P.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068008/
https://ncbi.nlm.nih.gov/pubmed/23203020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.337
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