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MicroRNA-204 Deficiency in Human Aortic Valves Elevates Valvular Osteogenic Activity

Aortic valve interstitial cells (AVICs) play a major role in valvular calcification associated with calcific aortic valve disease (CAVD). Although AVICs from diseased valves display a pro-osteogenic phenotype, the underlying mechanism causing this remains unclear. MicroRNA-204 (miR-204) is a negativ...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Song, Rui, Zhai, Yufeng, Ao, Lihua, Fullerton, David A., Meng, Xianzhong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981435/
https://ncbi.nlm.nih.gov/pubmed/31861929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010076
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