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Altered MicroRNA Expression Is Responsible for the Pro‐Osteogenic Phenotype of Interstitial Cells in Calcified Human Aortic Valves
BACKGROUND: The transition of aortic valve interstitial cells (AVICs) to myofibroblastic and osteoblast‐like phenotypes plays a critical role in calcific aortic valve disease progression. Several microRNAs (miRs) are implicated in stem cell differentiation into osteoblast. We hypothesized that an ep...
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| 發表在: | J Am Heart Assoc |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533027/ https://ncbi.nlm.nih.gov/pubmed/28438736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.005364 |
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