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pVHL-mediated regulation of the anti-angiogenic protein thrombospondin-1 decreases migration of Clear Cell Renal Carcinoma Cell Lines

Thrombospondin-1 (TSP-1) is a multifunctional matrix protein with antitumor activities due in part to its ability to inhibit angiogenesis, which in turn contributes to determine the fate of many tumours. Previous studies have shown that TSP-1 expression supports normal kidney angiostasis, and decrea...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Sevilla-Montero, Javier, Bienes-Martínez, Raquel, Labrousse-Arias, David, Fuertes-Yebra, Esther, Ordóñez, Ángel, Calzada, María J.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981148/
https://ncbi.nlm.nih.gov/pubmed/31980715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58137-w
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