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Autocrine stimulation of clear-cell renal carcinoma cell migration in hypoxia via HIF-independent suppression of thrombospondin-1

Thrombospondin-1 is a matricellular protein with potent antitumour activities, the levels of which determine the fate of many different tumours, including renal carcinomas. However, the factors that regulate this protein remain unclear. In renal carcinomas, hypoxic conditions enhance the expression...

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מידע ביבליוגרפי
Main Authors: Bienes-Martínez, Raquel, Ordóñez, Angel, Feijoo-Cuaresma, Mónica, Corral-Escariz, María, Mateo, Gloria, Stenina, Olga, Jiménez, Benilde, Calzada, María J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2012
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494377/
https://ncbi.nlm.nih.gov/pubmed/23145312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00788
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