Matricellular protein thrombospondin-1 in pulmonary hypertension: multiple pathways to disease

Por Rogers, Natasha M., Ghimire, Kedar, Calzada, Maria J., Isenberg, Jeffrey S.
Publicado no Cardiovasc Res (2017)

pVHL-mediated regulation of the anti-angiogenic protein thrombospondin-1 decreases migration of Clear Cell Renal Carcinoma Cell Lines

Por Sevilla-Montero, Javier, Bienes-Martínez, Raquel, Labrousse-Arias, David, Fuertes-Yebra, Esther, Ordóñez, Ángel, Calzada, María J.
Publicado no Sci Rep (2020)

Autocrine stimulation of clear-cell renal carcinoma cell migration in hypoxia via HIF-independent suppression of thrombospondin-1

Por Bienes-Martínez, Raquel, Ordóñez, Angel, Feijoo-Cuaresma, Mónica, Corral-Escariz, María, Mateo, Gloria, Stenina, Olga, Jiménez, Benilde, Calzada, María J.
Publicado em 2012

Interactions of thrombospondins with α4β1 integrin and CD47 differentially modulate T cell behavior

Por Li, Zhuqing, Calzada, Maria J., Sipes, John M., Cashel, Jo Anne, Krutzsch, Henry C., Annis, Douglas S., Mosher, Deane F., Roberts, David D.
Publicado em 2002

Calcium indirectly regulates immunochemical reactivity and functional activities of the N-domain of thrombospondin-1

Por Calzada, Maria J., Kuznetsova, Svetlana A., Sipes, John M., Rodrigues, Rui G., Cashel, Jo Anne, Annis, Douglas S., Mosher, Deane F., Roberts, David D.
Publicado em 2007

HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction

Por Labrousse-Arias, David, Castillo-González, Raquel, Rogers, Natasha M., Torres-Capelli, Mar, Barreira, Bianca, Aragonés, Julián, Cogolludo, Ángel, Isenberg, Jeffrey S., Calzada, María J.
Publicado no Cardiovasc Res (2016)

sFRP-1 binds via its netrin-related motif to the N-module of thrombospondin-1 and blocks thrombospondin-1 stimulation of MDA-MB-231 breast carcinoma cell adhesion and migration

Por Martin-Manso, Gema, Calzada, Maria J., Chuman, Yoshiro, Sipes, John M., Xavier, Charles P., Wolf, Vladimir, Kuznetsova, Svetlana A., Rubin, Jeffrey S., Roberts, David D.
Publicado em 2011

Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1

Por Bauer, Philip M., Bauer, Eileen M., Rogers, Natasha M., Yao, Mingyi, Feijoo-Cuaresma, Monica, Pilewski, Joseph M., Champion, Hunter C., Zuckerbraun, Brian S., Calzada, Maria J., Isenberg, Jeffrey S.
Publicado em 2012

Inadequate Activation of the GTPase RhoA Contributes to the Lack of Fibronectin Matrix Assembly in von Hippel-Lindau Protein-defective Renal Cancer Cells

Por Feijóo-Cuaresma, Monica, Méndez, Fernando, Maqueda, Alfredo, Esteban, Miguel A., Naranjo-Suarez, Salvador, Castellanos, Maria C., del Cerro, Mercedes Hernández, Vazquez, Silvia N., García-Pardo, Angeles, Landázuri, Manuel O., Calzada, Maria J.
Publicado em 2008

Thrombospondin-1/CD47 Interaction Regulates Th17 and Treg Differentiation in Psoriasis

Por Rodríguez-Jiménez, Pedro, Chicharro, Pablo, Llamas-Velasco, Mar, Cibrian, Danay, Trigo-Torres, Laura, Vara, Alicia, Jiménez-Fernández, María, Sevilla-Montero, Javier, Calzada, Maria J., Sánchez-Madrid, Francisco, de la Fuente, Hortensia, Daudén, Esteban
Publicado no Front Immunol (2019)

VHL promotes immune response against renal cell carcinoma via NF-κB–dependent regulation of VCAM-1

Por Labrousse-Arias, David, Martínez-Alonso, Emma, Corral-Escariz, María, Bienes-Martínez, Raquel, Berridy, Jaime, Serrano-Oviedo, Leticia, Conde, Elisa, García-Bermejo, María-Laura, Giménez-Bachs, José M., Salinas-Sánchez, Antonio S., Sánchez-Prieto, Ricardo, Yao, Masahiro, Lasa, Marina, Calzada, María J.
Publicado no J Cell Biol (2017)

TSP1–CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction

Por Rogers, Natasha M., Sharifi-Sanjani, Maryam, Yao, Mingyi, Ghimire, Kedar, Bienes-Martinez, Raquel, Mutchler, Stephanie M., Knupp, Heather E., Baust, Jeffrey, Novelli, Enrico M., Ross, Mark, St. Croix, Claudette, Kutten, Johannes C., Czajka, Caitlin A., Sembrat, John C., Rojas, Mauricio, Labrousse-Arias, David, Bachman, Timothy N., Vanderpool, Rebecca R., Zuckerbraun, Brian S., Champion, Hunter C., Mora, Ana L., Straub, Adam C., Bilonick, Richard A., Calzada, Maria J., Isenberg, Jeffrey S.
Publicado no Cardiovasc Res (2017)

COVID-19 severity associates with pulmonary redistribution of CD1c(+) DCs and inflammatory transitional and nonclassical monocytes

Por Sánchez-Cerrillo, Ildefonso, Landete, Pedro, Aldave, Beatriz, Sánchez-Alonso, Santiago, Sánchez-Azofra, Ana, Marcos-Jiménez, Ana, Ávalos, Elena, Alcaraz-Serna, Ana, de los Santos, Ignacio, Mateu-Albero, Tamara, Esparcia, Laura, López-Sanz, Celia, Martínez-Fleta, Pedro, Gabrie, Ligia, del Campo Guerola, Luciana, de la Fuente, Hortensia, Calzada, María J., González-Álvaro, Isidoro, Alfranca, Arantzazu, Sánchez-Madrid, Francisco, Muñoz-Calleja, Cecilia, Soriano, Joan B., Ancochea, Julio, Martín-Gayo, Enrique
Publicado no J Clin Invest (2020)