The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1

Por Meijles, Daniel N., Sahoo, Sanghamitra, Al Ghouleh, Imad, Amaral, Jefferson H., Bienes-Martinez, Raquel, Knupp, Heather E., Attaran, Shireen, Sembrat, John C., Nouraie, Seyed M., Rojas, Mauricio M., Novelli, Enrico M., Gladwin, Mark T., Isenberg, Jeffrey S., Cifuentes-Pagano, Eugenia, Pagano, Patrick J.
Publicado no Sci Signal (2017)

TSP1–CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction

Por Rogers, Natasha M., Sharifi-Sanjani, Maryam, Yao, Mingyi, Ghimire, Kedar, Bienes-Martinez, Raquel, Mutchler, Stephanie M., Knupp, Heather E., Baust, Jeffrey, Novelli, Enrico M., Ross, Mark, St. Croix, Claudette, Kutten, Johannes C., Czajka, Caitlin A., Sembrat, John C., Rojas, Mauricio, Labrousse-Arias, David, Bachman, Timothy N., Vanderpool, Rebecca R., Zuckerbraun, Brian S., Champion, Hunter C., Mora, Ana L., Straub, Adam C., Bilonick, Richard A., Calzada, Maria J., Isenberg, Jeffrey S.
Publicado no Cardiovasc Res (2017)