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Three Autocrine Feedback Loops Determine HIF1α Expression in Chronic Hypoxia

Hypoxia occurs in cancer, prolonged exercise, and long-term ischemia with durations of several hours or more, and the hypoxia-inducible factor 1 (HIF1) pathway response to these conditions differs from responses to transient hypoxia. We used computational modeling, validated by experiments, to gain...

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Bibliografische gegevens
Hoofdauteurs: Qutub, Amina A., Popel, Aleksander S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094118/
https://ncbi.nlm.nih.gov/pubmed/17720260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2007.07.004
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