Penetrance of different cancer types in families with Li-Fraumeni syndrome: a validation study using multi-center cohorts

Li-Fraumeni syndrome (LFS) is a rare hereditary cancer syndrome associated with an autosomal dominant mutation inheritance in the TP53 tumor suppressor gene and a wide spectrum of cancer diagnoses. The previously developed R package, LFSPRO, is capable of estimating the risk of an individual being a...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cancer Res
Hlavní autoři: Shin, Seung Jun, Dodd-Eaton, Elissa B., Peng, Gang, Bojadzieva, Jasmina, Chen, Jingxiao, Amos, Christopher I., Frone, Megan N., Khincha, Payal, Mai, Phuong L., Savage, Sharon A., Ballinger, Mandy L., Thomas, David M., Yuan, Ying, Strong, Louise C., Wang, Wenyi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980689/
https://ncbi.nlm.nih.gov/pubmed/31719101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0728
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky