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Bayesian estimation of a semiparametric recurrent event model with applications to the penetrance estimation of multiple primary cancers in Li-Fraumeni syndrome

A common phenomenon in cancer syndromes is for an individual to have multiple primary cancers (MPC) at different sites during his/her lifetime. Patients with Li-Fraumeni syndrome (LFS), a rare pediatric cancer syndrome mainly caused by germline TP53 mutations, are known to have a higher probability...

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Detalhes bibliográficos
Publicado no:Biostatistics
Main Authors: Shin, Seung Jun, Li, Jialu, Ning, Jing, Bojadzieva, Jasmina, Strong, Louise C, Wang, Wenyi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307969/
https://ncbi.nlm.nih.gov/pubmed/30445420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxy066
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