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Calcium/calmodulin-dependent kinase (CaMKII) Inhibition Protects against Purkinje Cell Damage Following CA/CPR in Mice

Ischemic brain damage is triggered by glutamate excitotoxicity resulting in neuronal cell death. Previous research has demonstrated that NMDA receptor activation triggers downstream calcium-dependent signaling pathways, specifically Ca2+/calmodulin-dependent protein kinase II (CaMKII). Inhibiting Ca...

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Dades bibliogràfiques
Publicat a:Mol Neurobiol
Autors principals: Chalmers, Nicholas, Yonchek, Joan, Steklac, Katie, Ramsey, Matthew, Bayer, K. Ulrich, Herson, Paco S., Quillinan, Nidia
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980452/
https://ncbi.nlm.nih.gov/pubmed/31520314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-01765-9
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