CaMKII Autonomy Is Substrate-dependent and Further Stimulated by Ca(2+)/Calmodulin

A hallmark feature of Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII) regulation is the generation of Ca(2+)-independent autonomous activity by Thr-286 autophosphorylation. CaMKII autonomy has been regarded a form of molecular memory and is indeed important in neuronal plasticity and le...

Full description

Saved in:
Bibliographic Details
Main Authors: Coultrap, Steven J., Buard, Isabelle, Kulbe, Jaqueline R., Dell'Acqua, Mark L., Bayer, K. Ulrich
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878555/
https://ncbi.nlm.nih.gov/pubmed/20353941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.069351
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items