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CaMKII Autonomy Is Substrate-dependent and Further Stimulated by Ca(2+)/Calmodulin
A hallmark feature of Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII) regulation is the generation of Ca(2+)-independent autonomous activity by Thr-286 autophosphorylation. CaMKII autonomy has been regarded a form of molecular memory and is indeed important in neuronal plasticity and le...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878555/ https://ncbi.nlm.nih.gov/pubmed/20353941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.069351 |
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