Synthesis and Biological Evaluation of Fluorescent Bryostatin Analogues

To investigate the cellular distribution of tumor-promoting vs. non-tumor-promoting bryostatin analogues, we synthesized fluorescently labeled variants of two bryostatin derivatives that have previously shown either phorbol ester-like or bryostatin-like biological activity in U937 leukemia cells. Th...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Cummins, Thomas J., Kedei, Noemi, Czikora, Agnes, Lewin, Nancy E., Kirk, Sharon, Petersen, Mark E., McGowan, Kevin M., Chen, Jin-Qiu, Luo, Xiaoling, Johnson, Randall C., Ravichandran, Sarangan, Blumberg, Peter M., Keck, Gary E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980389/
https://ncbi.nlm.nih.gov/pubmed/29424951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700655
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