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Role of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Axis in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is primarily diagnosed in the latter stages of disease progression and is the third leading cause of cancer deaths worldwide. Thus, there is a need to find biomarkers of early HCC as well as the development of more effective treatments for the disease. Sphingosine-1-ph...

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Bibliographic Details
Published in:Handb Exp Pharmacol
Main Authors: Maceyka, Michael, Rohrbach, Timothy, Milstien, Sheldon, Spiegel, Sarah
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980368/
https://ncbi.nlm.nih.gov/pubmed/31321542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/164_2019_217
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