Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake

p62/SQSTM1 is an autophagy receptor and signaling adaptor with an N-terminal PB1 domain that forms the scaffold of phase-separated p62 bodies in the cell. The molecular determinants that govern PB1 domain filament formation in vitro remain to be determined and the role of p62 filaments inside the ce...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Jakobi, Arjen J., Huber, Stefan T., Mortensen, Simon A., Schultz, Sebastian W., Palara, Anthimi, Kuhm, Tanja, Shrestha, Birendra Kumar, Lamark, Trond, Hagen, Wim J. H., Wilmanns, Matthias, Johansen, Terje, Brech, Andreas, Sachse, Carsten
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978347/
https://ncbi.nlm.nih.gov/pubmed/31974402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14343-8
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items