Fluoxetine Induces Apoptotic and Oxidative Neuronal Death Associated with The Influx of Copper Ions in Cultured Neuronal Cells

We examined the effect of fluoxetine, a selective serotonin reuptake inhibitor antidepressant, on neuronal viability in mouse cortical near-pure neuronal cultures. Addition of fluoxetine to the media for 24 hours induced neuronal death in a concentration-dependent manner. To delineate the mechanisms...

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Vydáno v:Chonnam Med J
Hlavní autoři: Hwang, Shinae, Kim, Jong-Keun
Médium: Artigo
Jazyk:Inglês
Vydáno: Chonnam National University Medical School 2020
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976768/
https://ncbi.nlm.nih.gov/pubmed/32021838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4068/cmj.2020.56.1.20
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