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Fluoxetine Induces Apoptotic and Oxidative Neuronal Death Associated with The Influx of Copper Ions in Cultured Neuronal Cells

We examined the effect of fluoxetine, a selective serotonin reuptake inhibitor antidepressant, on neuronal viability in mouse cortical near-pure neuronal cultures. Addition of fluoxetine to the media for 24 hours induced neuronal death in a concentration-dependent manner. To delineate the mechanisms...

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Detalhes bibliográficos
Publicado no:Chonnam Med J
Main Authors: Hwang, Shinae, Kim, Jong-Keun
Formato: Artigo
Idioma:Inglês
Publicado em: Chonnam National University Medical School 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976768/
https://ncbi.nlm.nih.gov/pubmed/32021838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4068/cmj.2020.56.1.20
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