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NADPH Oxidase Mediates β-Amyloid Peptide-Induced Neuronal Death in Mouse Cortical Cultures

β-Amyloid peptide (Aβ) is the main component of senile plaques in patients with Alzheimer's disease, and is known to be a main pathogenic factor of the disease. Recent evidence indicates that activation of NADPH oxidase (NOX) in microglia or astrocytes may be a source of Aβ-induced reactive oxy...

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Bibliografiske detaljer
Udgivet i:Chonnam Med J
Main Authors: Chay, Kee-Oh, Nam Koong, Kyoung Young, Hwang, Shinae, Kim, Jong-Keun, Bae, Choon Sang
Format: Artigo
Sprog:Inglês
Udgivet: Chonnam National University Medical School 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636758/
https://ncbi.nlm.nih.gov/pubmed/29026707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4068/cmj.2017.53.3.196
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