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Effects of NADPH Oxidase Inhibitors and Mitochondria-Targeted Antioxidants on Amyloid β(1-42)-Induced Neuronal Deaths in Mouse Mixed Cortical Cultures

The Amyloid β peptide (Aβ) is a main component of senile plaques in Alzheimer's disease. Currently, NADPH oxidase (NOX) and mitochondria are considered as primary sources of ROS induced by Aβ. However, the contribution of NOX and mitochondria to Aβ-induced ROS generation has not been well defin...

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Опубликовано в: :Chonnam Med J
Главные авторы: Hwang, Shinae, Kim, Jong-Keun
Формат: Artigo
Язык:Inglês
Опубликовано: Chonnam National University Medical School 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165920/
https://ncbi.nlm.nih.gov/pubmed/30288371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4068/cmj.2018.54.3.159
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