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The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides
Amyloid beta peptide (Aβ) accumulates in the CNS in Alzheimer's disease. Both the full peptide (1–42) or the 25–35 fragment are toxic to neurons in culture. We have used fluorescence imaging technology to explore the mechanism of neurotoxicity in mixed asytrocyte/neuronal cultures prepared from...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Royal Society
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569597/ https://ncbi.nlm.nih.gov/pubmed/16321801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2005.1766 |
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