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The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides

Amyloid beta peptide (Aβ) accumulates in the CNS in Alzheimer's disease. Both the full peptide (1–42) or the 25–35 fragment are toxic to neurons in culture. We have used fluorescence imaging technology to explore the mechanism of neurotoxicity in mixed asytrocyte/neuronal cultures prepared from...

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Detalles Bibliográficos
Main Authors: Abramov, Andrey Y, Duchen, Michael R
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569597/
https://ncbi.nlm.nih.gov/pubmed/16321801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2005.1766
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