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Changes in Intracellular Calcium and Glutathione in Astrocytes as the Primary Mechanism of Amyloid Neurotoxicity

Although the accumulation of the neurotoxic peptide β amyloid (βA) in the CNS is a hallmark of Alzheimer's disease, the mechanism of βA neurotoxicity remains controversial. In cultures of mixed neurons and astrocytes, we found that both the full-length peptide βA (1–42) and the neurotoxic fragm...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Abramov, Andrey Y., Canevari, Laura, Duchen, Michael R.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741151/
https://ncbi.nlm.nih.gov/pubmed/12832532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-12-05088.2003
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