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Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming
In humans, chronic glucocorticoid use is associated with side effects like muscle wasting, obesity, and metabolic syndrome. Intermittent steroid dosing has been proposed in Duchenne Muscular Dystrophy patients to mitigate the side effects seen with daily steroid intake. We evaluated biomarkers from...
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| Pubblicato in: | JCI Insight |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6975267/ https://ncbi.nlm.nih.gov/pubmed/31852847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.132402 |
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