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Epigenetic reprogramming to prevent genetic cardiomyopathy

Mutations in the gene that codes for lamin A/C (LMNA) are a common cause of adult-onset cardiomyopathy and heart failure. In this issue of the JCI, Guénantin and Jebeniani et al. identify impaired cardiomyocyte development and maturation as a prenatal feature in a model of laminopathy. Cardiomyocyte...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Johnston, Jamie R., Selgrade, Daniel F., McNally, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773388/
https://ncbi.nlm.nih.gov/pubmed/33393498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI143684
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