Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming

In humans, chronic glucocorticoid use is associated with side effects like muscle wasting, obesity, and metabolic syndrome. Intermittent steroid dosing has been proposed in Duchenne Muscular Dystrophy patients to mitigate the side effects seen with daily steroid intake. We evaluated biomarkers from...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Quattrocelli, Mattia, Zelikovich, Aaron S., Jiang, Zhen, Peek, Clara Bien, Demonbreun, Alexis R., Kuntz, Nancy L., Barish, Grant D., Haldar, Saptarsi M., Bass, Joseph, McNally, Elizabeth M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975267/
https://ncbi.nlm.nih.gov/pubmed/31852847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.132402
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