mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging

Cerebrovascular dysfunction and cognitive decline are highly prevalent in aging, but the mechanisms underlying these impairments are unclear. Cerebral blood flow decreases with aging and is one of the earliest events in the pathogenesis of Alzheimer's disease (AD). We have previously shown that...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Aging Cell
Main Authors: Van Skike, Candice E., Lin, Ai‐Ling, Roberts Burbank, Raquel, Halloran, Jonathan J., Hernandez, Stephen F., Cuvillier, James, Soto, Vanessa Y., Hussong, Stacy A., Jahrling, Jordan B., Javors, Martin A., Hart, Matthew J., Fischer, Kathleen E., Austad, Steven N., Galvan, Veronica
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974719/
https://ncbi.nlm.nih.gov/pubmed/31693798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13057
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