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Rationale and Roadmap for Developing Panels of Hotspot Cancer Driver Gene Mutations as Biomarkers of Cancer Risk

Cancer driver mutations (CDMs) are necessary and causal for carcinogenesis and have advantages as reporters of carcinogenic risk. However, little progress has been made toward developing measurements of CDMs as biomarkers for use in cancer risk assessment. Impediments for using a CDM‐based metric to...

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Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Harris, Kelly L., Myers, Meagan B., McKim, Karen L., Elespuru, Rosalie K., Parsons, Barbara L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973253/
https://ncbi.nlm.nih.gov/pubmed/31469467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22326
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