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Variation in organ‐specific PIK3CA and KRAS mutant levels in normal human tissues correlates with mutation prevalence in corresponding carcinomas

Large‐scale sequencing efforts have described the mutational complexity of individual cancers and identified mutations prevalent in different cancers. As a complementary approach, allele‐specific competitive blocker PCR (ACB‐PCR) is being used to quantify levels of hotspot cancer driver mutations (C...

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Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Parsons, Barbara L., McKim, Karen L., Myers, Meagan B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601221/
https://ncbi.nlm.nih.gov/pubmed/28755461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22110
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