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Variation in organ‐specific PIK3CA and KRAS mutant levels in normal human tissues correlates with mutation prevalence in corresponding carcinomas

Large‐scale sequencing efforts have described the mutational complexity of individual cancers and identified mutations prevalent in different cancers. As a complementary approach, allele‐specific competitive blocker PCR (ACB‐PCR) is being used to quantify levels of hotspot cancer driver mutations (C...

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Détails bibliographiques
Publié dans:Environ Mol Mutagen
Auteurs principaux: Parsons, Barbara L., McKim, Karen L., Myers, Meagan B.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601221/
https://ncbi.nlm.nih.gov/pubmed/28755461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22110
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