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Low-frequency KRAS mutations are prevalent in lung adenocarcinomas

AIM: This study quantified low-frequency KRAS mutations in normal lung and lung adenocarcinomas, to understand their potential significance in the development of acquired resistance to EGFR-targeted therapies. MATERIALS & METHODS: Allele-specific Competitive Blocker-PCR was used to quantify KRAS...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Per Med
Egile Nagusiak: Myers, Meagan B, McKim, Karen L, Meng, Fanxue, Parsons, Barbara L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084916/
https://ncbi.nlm.nih.gov/pubmed/27795727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pme.14.69
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