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Low-frequency KRAS mutations are prevalent in lung adenocarcinomas
AIM: This study quantified low-frequency KRAS mutations in normal lung and lung adenocarcinomas, to understand their potential significance in the development of acquired resistance to EGFR-targeted therapies. MATERIALS & METHODS: Allele-specific Competitive Blocker-PCR was used to quantify KRAS...
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| Publicado no: | Per Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5084916/ https://ncbi.nlm.nih.gov/pubmed/27795727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pme.14.69 |
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