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Frequency of EGFR and KRAS Mutations in Lung Adenocarcinomas in African-Americans
INTRODUCTION: The detection of mutations in the epidermal growth factor receptor (EGFR) gene, which predict sensitivity to treatment with EGFR tyrosine kinase inhibitors (TKIs), represents a major advance in the treatment of lung adenocarcinoma. KRAS mutations confer resistance to EGFR -TKIs. The pr...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337520/ https://ncbi.nlm.nih.gov/pubmed/21107288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3181fb4fe2 |
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