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Association of KRAS and EGFR Mutations with Survival in Patients with Advanced Lung Adenocarcinomas

BACKGROUND: Lung adenocarcinomas can be distinguished by identifying mutated driver oncogenes including EGFR and KRAS. Mutations in EGFR are associated with both an improved survival as well as response to treatment with erlotinib and gefitinib. However, the prognostic significance of KRAS has not b...

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Detalhes bibliográficos
Main Authors: Johnson, Melissa L., Sima, Camelia S., Chaft, Jamie, Paik, Paul K., Pao, William, Kris, Mark G., Ladanyi, Marc, Riely, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966555/
https://ncbi.nlm.nih.gov/pubmed/22810899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27730
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