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Association of KRAS and EGFR Mutations with Survival in Patients with Advanced Lung Adenocarcinomas

BACKGROUND: Lung adenocarcinomas can be distinguished by identifying mutated driver oncogenes including EGFR and KRAS. Mutations in EGFR are associated with both an improved survival as well as response to treatment with erlotinib and gefitinib. However, the prognostic significance of KRAS has not b...

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Bibliografiske detaljer
Main Authors: Johnson, Melissa L., Sima, Camelia S., Chaft, Jamie, Paik, Paul K., Pao, William, Kris, Mark G., Ladanyi, Marc, Riely, Gregory J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966555/
https://ncbi.nlm.nih.gov/pubmed/22810899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27730
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