Molecular Epidemiology of EGFR and KRAS Mutations in 3026 Lung Adenocarcinomas: Higher Susceptibility of Women to Smoking-related KRAS-mutant Cancers

PURPOSE: The molecular epidemiology of most EGFR and KRAS mutations in lung cancer remains unclear. EXPERIMENTAL DESIGN: We genotyped 3026 lung adenocarcinomas for the major EGFR (exon 19 deletions and L858R) and KRAS (G12, G13) mutations and examined correlations with demographic, clinical and smok...

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Hoofdauteurs: Dogan, Snjezana, Shen, Ronglai, Ang, Daphne C, Johnson, Melissa L, D’Angelo, Sandra P, Paik, Paul K, Brzostowski, Edyta B, Riely, Gregory J, Kris, Mark G, Zakowski, Maureen F, Ladanyi, Marc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500422/
https://ncbi.nlm.nih.gov/pubmed/23014527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3265
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