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Association of KRAS and EGFR Mutations with Survival in Patients with Advanced Lung Adenocarcinomas

BACKGROUND: Lung adenocarcinomas can be distinguished by identifying mutated driver oncogenes including EGFR and KRAS. Mutations in EGFR are associated with both an improved survival as well as response to treatment with erlotinib and gefitinib. However, the prognostic significance of KRAS has not b...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Johnson, Melissa L., Sima, Camelia S., Chaft, Jamie, Paik, Paul K., Pao, William, Kris, Mark G., Ladanyi, Marc, Riely, Gregory J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966555/
https://ncbi.nlm.nih.gov/pubmed/22810899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27730
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