Frequency of EGFR and KRAS Mutations in Lung Adenocarcinomas in African-Americans

INTRODUCTION: The detection of mutations in the epidermal growth factor receptor (EGFR) gene, which predict sensitivity to treatment with EGFR tyrosine kinase inhibitors (TKIs), represents a major advance in the treatment of lung adenocarcinoma. KRAS mutations confer resistance to EGFR -TKIs. The pr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Reinersman, J. Matthew, Johnson, Melissa L., Riely, Gregory J., Chitale, Dhananjay A., Nicastri, Anthony D., Soff, Gerald A., Schwartz, Ann G., Sima, Camelia S., Ayalew, Getinet, Lau, Christopher, Zakowski, Maureen F., Rusch, Valerie W., Ladanyi, Marc, Kris, Mark G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337520/
https://ncbi.nlm.nih.gov/pubmed/21107288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3181fb4fe2
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