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KRAS mutant tumor subpopulations can subvert durable responses to personalized cancer treatments

KRAS mutations in colorectal and lung cancers predict failure to respond to therapies that target the EGFR. Significant percentages of patients with KRAS wild-type tumors also fail to respond to these therapies. Relapse occurs in patients with KRAS wild-type and mutant tumors, with moderately longer...

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Detalhes bibliográficos
Publicado no:Per Med
Main Authors: Parsons, Barbara L, Myers, Meagan B
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115778/
https://ncbi.nlm.nih.gov/pubmed/27867401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pme.13.1
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