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KRAS mutant colorectal tumors: Past and present

The treatment of metastatic colorectal cancer (mCRC) remains one of the largest hurdles in cancer therapeutics to date. The most advanced treatment option for mCRC patients are anti-epidermal growth factor receptor (EGFR) monoclonal antibodies (mAbs) that bind to and inhibit the activity of EGFR. Wh...

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Detalhes bibliográficos
Main Authors: Brand, Toni M., Wheeler, Deric L.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398915/
https://ncbi.nlm.nih.gov/pubmed/22714415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.18751
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