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KRAS mutant tumor subpopulations can subvert durable responses to personalized cancer treatments

KRAS mutations in colorectal and lung cancers predict failure to respond to therapies that target the EGFR. Significant percentages of patients with KRAS wild-type tumors also fail to respond to these therapies. Relapse occurs in patients with KRAS wild-type and mutant tumors, with moderately longer...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Per Med
Asıl Yazarlar: Parsons, Barbara L, Myers, Meagan B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115778/
https://ncbi.nlm.nih.gov/pubmed/27867401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pme.13.1
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