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Rationale and Roadmap for Developing Panels of Hotspot Cancer Driver Gene Mutations as Biomarkers of Cancer Risk

Cancer driver mutations (CDMs) are necessary and causal for carcinogenesis and have advantages as reporters of carcinogenic risk. However, little progress has been made toward developing measurements of CDMs as biomarkers for use in cancer risk assessment. Impediments for using a CDM‐based metric to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Environ Mol Mutagen
Hauptverfasser: Harris, Kelly L., Myers, Meagan B., McKim, Karen L., Elespuru, Rosalie K., Parsons, Barbara L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973253/
https://ncbi.nlm.nih.gov/pubmed/31469467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22326
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