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Site‐Specific Encoding of Photoactivity in Antibodies Enables Light‐Mediated Antibody–Antigen Binding on Live Cells

Antibodies have found applications in several fields, including, medicine, diagnostics, and nanotechnology, yet methods to modulate antibody–antigen binding using an external agent remain limited. Here, we have developed photoactive antibody fragments by genetic site‐specific replacement of single t...

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Bibliografische gegevens
Gepubliceerd in:Angew Chem Int Ed Engl
Hoofdauteurs: Bridge, Thomas, Shaikh, Saher A., Thomas, Paul, Botta, Joaquin, McCormick, Peter J., Sachdeva, Amit
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973043/
https://ncbi.nlm.nih.gov/pubmed/31609054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201908655
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