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Cyanine Photocages Enable the Near-IR Light Activation of Antibody-Drug Conjugates
Despite significant progress in the clinical application of antibody drug conjugates (ADCs), novel cleavage strategies that provide improved selectivity are still needed. Near-IR light could provide a targetable, biocompatible external stimulus to initiate drug release. Here we report the first appr...
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| 發表在: | Angew Chem Int Ed Engl |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743669/ https://ncbi.nlm.nih.gov/pubmed/26403799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201507391 |
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