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Cyanine Photocages Enable the Near-IR Light Activation of Antibody-Drug Conjugates
Despite significant progress in the clinical application of antibody drug conjugates (ADCs), novel cleavage strategies that provide improved selectivity are still needed. Near-IR light could provide a targetable, biocompatible external stimulus to initiate drug release. Here we report the first appr...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743669/ https://ncbi.nlm.nih.gov/pubmed/26403799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201507391 |
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