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Site‐Specific Encoding of Photoactivity in Antibodies Enables Light‐Mediated Antibody–Antigen Binding on Live Cells

Antibodies have found applications in several fields, including, medicine, diagnostics, and nanotechnology, yet methods to modulate antibody–antigen binding using an external agent remain limited. Here, we have developed photoactive antibody fragments by genetic site‐specific replacement of single t...

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書誌詳細
出版年:Angew Chem Int Ed Engl
主要な著者: Bridge, Thomas, Shaikh, Saher A., Thomas, Paul, Botta, Joaquin, McCormick, Peter J., Sachdeva, Amit
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973043/
https://ncbi.nlm.nih.gov/pubmed/31609054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201908655
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