Site‐Specific Encoding of Photoactivity in Antibodies Enables Light‐Mediated Antibody–Antigen Binding on Live Cells

Antibodies have found applications in several fields, including, medicine, diagnostics, and nanotechnology, yet methods to modulate antibody–antigen binding using an external agent remain limited. Here, we have developed photoactive antibody fragments by genetic site‐specific replacement of single t...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Bridge, Thomas, Shaikh, Saher A., Thomas, Paul, Botta, Joaquin, McCormick, Peter J., Sachdeva, Amit
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973043/
https://ncbi.nlm.nih.gov/pubmed/31609054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201908655
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